MObyDiCK platform
MObyDiCK (Mechanistic Target Optimization by Discovering and Controlling Network) platform is one of innovative and revolutionary products of our research from the last two decades, which incorporates systems biology and network control theories to identify first-in-class targets that can revert cancer and aged cells into normal and healthy cells. Using this, various experimental data, including single-cell omics data, can be incorporated to construct context-specific mathematic models for conducting extensive computational simulations in order to decipher underlying mechanisms of cancer and aging.
Pipeline
Disease | Modality | Early development | Middle development | Late development | Pre-clinical | Clinical I/II | Clinical III | Partnership | |
---|---|---|---|---|---|---|---|---|---|
BRVT101 | Hepatocellular carcinoma | ASO | |||||||
BRVT121 | Hepatocellular carcinoma | Small molecule | |||||||
BRVT231 | Lung adenocarcinoma | Small molecule | |||||||
BRVT221 | Lung cancer (I/O) | Small molecule | |||||||
BRVT321 | Colorectal cancer | Small molecule | |||||||
BRVT301 | Colorectal cancer | AAV |